Multicentric Metaplastic Breast Carcinoma with Squamous Differentiation
Published: July 1, 2015 | DOI: https://doi.org/10.7860/JCDR/2015/.6218
Sunil Vitthalrao Jagtap, Suresh J. Bhosale, P.G.Chougule, Shrutika D Dhawan, Dhiraj Shukla
1. Professor, Department of Pathology, Krishna Institute of Medical Sciences University, Karad, Maharashtra, India.
2. Professor, Department of Surgery, Krishna Institute of Medical Sciences University, Karad, Maharashtra, India.
3. Professor, Department of Surgery, Krishna Institute of Medical Sciences University, Karad, Maharashtra, India.
4. Assistant Lecturer, Department of Pathology, Krishna Institute of Medical Sciences University, Karad, Maharashtra, India.
5. Assistant Lecturer, Department of Pathology, Krishna Institute of Medical Sciences University, Karad, Maharashtra, India.
Correspondence
Dr. Sunil V Jagtap,
Professor, Department of Pathology, Krishna Institute of Medical Sciences University, Karad, Maharashtra, India.
E-mail: drsvjagtap@gmail.com
Metaplastic breast carcinoma is a rare primary breast malignancy. A 45-year-old female patient presented with multicentric lumps in left breast of 6 months duration and history of axillary lymphadenopathy of 2 months duration. Mammography revealed two high density masses with ill defined margins. Fine needle aspiration cytology was positive for duct carcinoma cells. Histo pathologic examination, reported as “Multicentric infiltrating duct carcinoma with squamous differentiation left breast”, grade 2. Immunohistochemistry revealed negativity for ER, PR and positivity for HER-2neu. We are presenting this rare case for clinical, radiological, histopathological and immunohistochemical study.
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